Overview

Understanding Lung Disease in Children with Esophageal Atresia and Tracheomalacia

Tralulala is a national Danish research project focused on understanding respiratory complications in children born with esophageal atresia (EA) – a rare congenital malformation often accompanied by tracheomalacia (TM).

While survival and surgical outcomes have improved significantly in recent decades, many children experience long-term respiratory symptoms such as wheezing, coughing, and exercise intolerance. However, respiratory disease remains understudied in this population.

We aim to:

  • Describe the burden of respiratory disease
  • Improve our understanding of the underlying airway abnormalities
  • Develop better tools for diagnosis and follow-up
  • Guide future treatment strategies and clinical care

Our research is rooted in clinical practice and designed to benefit children directly. We work closely with families, clinicians, and researchers to build a comprehensive understanding of airway disease in this vulnerable population.

🧒 Centered on the child

📅 Timeline (short version)

YearActivity
2023Register study and pilot study initiated
2024Pilot study completed
2025National cross-sectional study launched
2026–2027Data collection and analysis
2027–2028Biomarker study and long-term follow-up